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Agar.io is an amateur clone of the popular game "Spore", featuring an online, real-time multi-player gameplay, where instead of facing off against the computer, you face off with real competitors from across the world.
In Agar.io, you start off as a small cell, collecting pickups and eating smaller creatures with a goal of growing larger and larger until you make it to the leaderboards. From the leaderboards, it's matter of trying to survive for as long as possible.
So how do you beat this game and get to the top of the leaderboard of your current "room"?
1) You're going to need patience.When you play Agar.io, you must be committed to playing the game before you even think about getting on the leaderboards.
This is because the longer you play, the more the opportunities will pop-up. Yet, at the same time, extended play means a higher risk of losing everything that you have gained to another player.
3 hours of gameplay seems like a good time-frame.
Whatever way you look at it, Agar.io is going to be a game of patience, hence sometimes, the best move to play is to not play at all.
2) Not moving at all.When you start small, hiding behind the solid "green" cells can test the patience of the player stalking you, and eventually, another player will eat them up, or they lose patience and find another target.
To "not move at all", align your mouse to precisely the centre of your screen, right click at that location, and well...You're surviving!
3) There might be skill involved.You're going to be moving constantly around the board once you reach the size where the solid "green" cells can split you. So be sure to dodge the larger cells, and eat up as many small cells as possible. With a larger cell, take care to draw them into the solid "green" cells, as you can still hide behind them (just not within them).
Make sure also, that you have good motor control of your cell. That means that your mouse has to be ultra-responsive and your Internet should be able to handle the real-time connection without stuttering or lag. Your hand should gently guide your mouse around, as a cell travelling in a straight line will be faster than in zig-zags.
4) Do not divide.I cannot emphasise this more than enough, you can press "space" to divide/split, however if you're at a large cell size, it would be quite the challenge to merge back into a single, large cell again.
If other players split you when you're still small, then try to avoid those players, and attempt to grow to the size larger than their split.
5) Cornering.Once you're large, stake out each and every one of the corners constantly. You might be able to trap players and eat them up.
6) You're not going to lose!Even if a cell is chasing you is one level higher then you in the leaderboard (or about the same size as you). Judge if the cell is just about the same size as you - If so, they will not be able to eat you up, so just let them. Since there's no harm in doing so. (They will stack on top of you, but that's it).
7) Move around to find victims.When you're a large cell, seek out those higher then you on the leaderboard. If they are divided, and your singular cell can eat a component of their split cells, then chase after it and absorb their split into your cell, which in turn grows you, and so you're able to eat their other components, and effectively, you have fully absorbed your target, and rise to the top of the leaderboard.
8) Understand how the splitting works.The two solid "green" cells near each other do not split you if your cell is smaller than the distance, plus the diameter of a "green" circle. There's a threshold of the amount of your cell that can touch/overlap the green cell until you actually split. So take that into consideration.
9) Understand how to merge split cells.To merge your divided cells, ensure that one cell is larger then the other, and move in a fashion that will allow the cells to eat each-other. If your divided cells are side-by-side, try moving vertically. Else, move horizontally if your sides are above and below each other.
10) Hug the boundary!Hugging the boundary is important for when you want to escape from a predator cell - particularly when there are solid "green" cells that you know can protect you.
At least 1/3 of your cell can overflow outside of boundary lines, which leads to an easy escape otherwise seemingly impossible.
You cell does not burst, or pop when you hug the boundary line, and hence becomes a crucial strategy to know in order to survive.
11) Have a friend, or more than a single monitor.You have a "feeder-leecher" system, where the feeder suicides to grow the leecher. In short, you have one monitor that is making the cell on the second monitor larger and larger.
The cell on the second monitor should be not moving at all, as demonstrated in 2)